Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017327 | 1.00 | GAA (0.43) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL28293435 | 0.89 | MAOA (0.45) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL1714866 | 0.85 | GAA (0.43) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL2808245 | 0.79 | GAA (0.58) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL4904341 | 0.76 | GAA (0.52) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL4896945 | 0.76 | GAA (0.52) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL2582409 | 0.75 | MAOA (0.38) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL1667749 | 0.75 | GAA (0.48) | GAALMNAMEN1KMT2APOLB | |
| SCHEMBL8610401 | 0.74 | — | — | |
| SCHEMBL4896837 | 0.74 | GAA (0.51) | GAALMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | disclosed |