⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045299 | 0.85 | — | — | |
| SCHEMBL29821784 | 0.85 | — | — | |
| SCHEMBL26049463 | 0.85 | — | — | |
| SCHEMBL24485365 | 0.85 | — | — | |
| SCHEMBL29017392 | 0.85 | — | — | |
| SCHEMBL8607807 | 0.84 | EPHX1 (0.39) | — | |
| SCHEMBL3301796 | 0.82 | EPHX1 (0.39) | — | |
| SCHEMBL30782062 | 0.80 | EPHX1 (0.32) | — | |
| SCHEMBL9516701 | 0.80 | EPHX1 (0.43) | — | |
| SCHEMBL1239755 | 0.76 | EPHX1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111582-A1 | AZA-TETRACYCLIC OXAZEPINE INHIBITORS OF KRAS-G12D | GENENTECH, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| US-20240140957-A1 | BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF | BEONE MEDICINES I GMBH (CH) | 2024-05-02 | — | — | US | disclosed |
| WO-2022148422-A1 | BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2022-07-14 | — | — | WO | disclosed |
| CN-112778507-B | Preparation method of hydrolysis-resistant hyperbranched polycaprolactone | 山东一诺威新材料有限公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-2794596-B1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER IP GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-5821391-A | HYDROGENATING 1,3-DIOXANES IN THE PRESENCE OF A CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5780686-A | REACTING 1,3-DIOXANES WITH AMMONIA AND HYDROGEN IN PRESENCE OF HYDROGENATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| US-5780687-A | REACTING 1,3-DIOXANES WITH HYDROGEN IN PRESENCE OF HYDROGENATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0810194-A1 | Process for preparing 3-oxyalkylpropan-1-ols | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| EP-0810202-A2 | Process for the preparation of 4-oxaamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| EP-0291806-B1 | TRANSFORMATION OF 1,3-DIOXANES INTO 4-OXA-ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| EP-0291807-B1 | TRANSFORMATION OF 1,3-DIOXANES INTO 4-OXA-ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-01-15 | — | — | EP | disclosed |
| EP-0199210-B1 | CONVERSION OF 1,3-DIOXANES INTO 4-OXA-ALDEHYDES | BASF Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-5012005-A | Catalytic isomerization using a metal oxide catalyst | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| US-4939280-A | Aluminum phosphate catalysts with zeolitic structure molcular sieves | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| EP-0291807-A1 | Transformation of 1,3-dioxanes into 4-oxa-aldehydes | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | disclosed |
| EP-0291806-A1 | Transformation of 1,3-dioxanes into 4-oxa-aldehydes | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4709097-A | CATALYTIC ISOMERIZATION WITH ACIDIC ZEOLITE | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |
| EP-0199210-A2 | Conversion of 1,3-dioxanes into 4-oxa-aldehydes | BASF Aktiengesellschaft (DE) | 1986-10-29 | — | — | EP | disclosed |