Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452204 | 0.82 | CNR2 (0.57) | CNR2 | |
| SCHEMBL29017644 | 0.82 | CNR2 (0.57) | DPP4CNR2HRH4IRAK4MAP4K4 | |
| SCHEMBL29017660 | 0.82 | PBRM1 (0.38) | CNR2 | |
| SCHEMBL29017783 | 0.81 | CNR2 (0.60) | DPP4CNR2 | |
| SCHEMBL29017678 | 0.78 | CNR2 (0.42) | DPP4CNR2IRAK4MAP4K4 | |
| SCHEMBL29017694 | 0.75 | CNR1 (0.47) | — | |
| SCHEMBL29637923 | 0.75 | CNR1 (0.47) | — | |
| SCHEMBL29637917 | 0.75 | KMT2A (0.44) | — | |
| SCHEMBL14566348 | 0.75 | CNR2 (0.69) | CNR2 | |
| SCHEMBL21788579 | 0.73 | MAP4K4 (0.48) | DPP4HRH4MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478478-B | N- (1- (6- (substituted phenyl) pyridazin-3-yl) piperidin-3-yl) amine/amide derivatives and process for preparing the same | 厦门大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114478478-A | N- (1- (6- (substituted phenyl) pyridazine-3-yl) piperidine-3-yl) amine/amide derivative and preparation method thereof | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |