Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566348 | 0.86 | CNR2 (0.69) | CNR2NPC1RAB9ATP53CNR1 | |
| SCHEMBL29017654 | 0.82 | DPP4 (0.44) | CNR2 | |
| SCHEMBL29017660 | 0.77 | PBRM1 (0.38) | CNR2CYP1A2 | |
| SCHEMBL27419635 | 0.73 | TP53 (0.59) | CNR2NPC1RAB9ALMNACYP1A2 | |
| SCHEMBL14051349 | 0.72 | CNR2 (1.00) | CNR2CYP1A2CNR1 | |
| SCHEMBL14566339 | 0.72 | CNR2 (1.00) | CNR2CYP1A2CNR1 | |
| SCHEMBL14503215 | 0.72 | CYP1A2 (0.75) | CNR2NPC1RAB9ALMNACYP1A2 | |
| SCHEMBL14051350 | 0.70 | CNR2 (0.75) | CNR2CYP1A2TP53CNR1 | |
| SCHEMBL6514775 | 0.69 | KEAP1 (0.53) | NPC1 | |
| Hydrochloric Acid SCHEMBL29156848 | 0.68 | KEAP1 (0.52) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478478-B | N- (1- (6- (substituted phenyl) pyridazin-3-yl) piperidin-3-yl) amine/amide derivatives and process for preparing the same | 厦门大学 | 2023-06-13 | — | — | CN | disclosed |