SCHEMBL290181

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23746266	0.90	S1PR1 (0.50)	HSD17B10MAPK1CDC7DBF4NPC1
	SCHEMBL290376	0.88	CYP1A2 (0.49)	HSD17B10MAPK1USP2CDC7DBF4
	SCHEMBL15047257	0.88	HSD17B10 (0.44)	HSD17B10MAPK1USP2CDC7DBF4
	SCHEMBL16653370	0.88	KDM4E (0.38)	HSD17B10MAPK1USP2CDC7DBF4
	SCHEMBL13048689	0.88	HSD17B10 (0.43)	HSD17B10MAPK1USP2CDC7DBF4
	SCHEMBL16660124	0.87	CYP3A4 (0.44)	HSD17B10CDC7DBF4NPC1RAB9A
	SCHEMBL290820	0.86	PAX8 (0.45)	HSD17B10CDC7DBF4ALDH1A1MAPT
	SCHEMBL23726147	0.86	HSD17B10 (0.48)	HSD17B10MAPK1USP2CDC7DBF4
	SCHEMBL13048880	0.85	NPC1 (0.46)	HSD17B10MAPK1USP2CDC7DBF4
	SCHEMBL13048095	0.82	DYRK1A (0.36)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.