SCHEMBL2901885

SCHEMBL2901885

CC(=O)OC1CCCC=CO1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
CHRM2 P08172 4/20 0.33
CHRM1 P11229 2/20 0.33
MEN1 O00255 1/20 0.33
CYP2D6 P10635 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRM4 P08173 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC18A3 Q16572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092499 0.89 TSHR (0.42) TSHRCHRM2CHRM1MEN1CYP2D6
SCHEMBL27809329 0.77
SCHEMBL3641088 0.72
SCHEMBL11637458 0.70 CHRM2 (0.33) CHRM2CHRM1CHRM4CHRM3
SCHEMBL19365113 0.70 TSHR (0.48) TSHRCHRM2CHRM1MEN1CYP2D6
SCHEMBL24884685 0.69 EPHX1 (0.36) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL18236939 0.69 EPHX1 (0.36) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL868024 0.69 EPHX1 (0.36) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL20839586 0.69 EPHX1 (0.36) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL868023 0.69 EPHX1 (0.36) CHRM2CHRM1MEN1CYP2D6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140219925-A1 POLYMER PARTICLES OR NANO-VECTORS AND USE THEREOF AS A DRUG AND/OR DIAGNOSTIC AGENT INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2014-08-07 US claimed
EP-1771492-B1 STIMULATEABLE POLYMER PARTICLES EXHIBITING REACTIVE FUNCTIONS, METHOD FOR THE PRODUCTION AND THE USE THEREOF CENTRE NAT RECH SCIENT (FR) 2010-11-10 EP claimed
EP-1758621-B1 BIOACTIVE BIOMATERIALS FOR CONTROLLED DELIVERY OF ACTIVE PRINCIPLES CENTRE NAT RECH SCIENT (FR) 2010-08-11 EP claimed
US-20090123555-A1 Stimulateable Polymer Particles Exhibiting Reactive Functions, Method for the Production and the Use Thereof CENTRE NATIONAL DE LA RECHER CHE SCIENTIFIQUE (FR) 2009-05-14 US claimed
US-20080004398-A1 Bioactive Biomaterials for Controlled Delivery of Active Principles UNIVERSITE DE BORDEAUX I (FR) 2008-01-03 US claimed
US-20170360947-A1 POLYMER PARTICLES AND BIOMATERIALS COMPRISING THE SAME Universite de Bordeaux (FR) 2017-12-21 US disclosed
EP-3237488-A1 POLYMER PARTICLES AND BIOMATERIALS COMPRISING THE SAME Université de Bordeaux (FR) 2017-11-01 EP disclosed
WO-2016097358-A1 POLYMER PARTICLES AND BIOMATERIALS COMPRISING THE SAME Universite de Bordeaux (FR) 2016-06-23 WO disclosed
EP-3034538-A1 Polymer particles and biomaterials comprising the same UNIVERSITE DE BORDEAUX (FR) 2016-06-22 EP disclosed
US-20140219925-A1 POLYMER PARTICLES OR NANO-VECTORS AND USE THEREOF AS A DRUG AND/OR DIAGNOSTIC AGENT INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2014-08-07 US disclosed
US-20090123555-A1 Stimulateable Polymer Particles Exhibiting Reactive Functions, Method for the Production and the Use Thereof CENTRE NATIONAL DE LA RECHER CHE SCIENTIFIQUE (FR) 2009-05-14 US disclosed
US-20080004398-A1 Bioactive Biomaterials for Controlled Delivery of Active Principles UNIVERSITE DE BORDEAUX I (FR) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360947-A1 POLYMER PARTICLES AND BIOMATERIALS COMPRISING THE SAME CD47, INCENP, BAG6 TSHR 4816/4885CHRM2 4422/4885CHRM1 4313/4885
US-20140219925-A1 POLYMER PARTICLES OR NANO-VECTORS AND USE THEREOF AS A DRUG AND/OR DIAGNOSTIC AGENT ABCB1, TSG101, CD44 TSHR 3386/4885CHRM2 4761/4885CHRM1 4775/4885
US-20090123555-A1 Stimulateable Polymer Particles Exhibiting Reactive Functions, Method for the Production and the Use Thereof PMAIP1, ACP1, CD40 TSHR 1511/4885CHRM2 1280/4885CHRM1 859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.