Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29019096 | 0.93 | TP53 (0.33) | TP53F2NOS1NOS2DPP8 | |
| Trifluoroacetic Acid SCHEMBL29019093 | 0.87 | TP53 (0.40) | TP53NOS1NOS2DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL3140803 | 0.87 | TP53 (0.44) | TP53DPP8DPP7DPP4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7764428 | 0.87 | ACHE (0.38) | TP53F2F11PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL2409655 | 0.87 | ACHE (0.38) | TP53F2F11PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL31438646 | 0.87 | ACHE (0.38) | TP53F2F11PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7793452 | 0.84 | TP53 (0.42) | TP53DPP8DPP7DPP4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL1035693 | 0.84 | TP53 (0.42) | TP53DPP8DPP7DPP4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29019094 | 0.83 | TP53 (0.33) | TP53DPP8DPP7DPP4 | |
| Trifluoroacetic Acid SCHEMBL20984227 | 0.82 | TP53 (0.43) | TP53F2F11PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115915795-A | Perovskite solar cell containing double-layer trifluoroacetate modification layer and preparation method thereof | 河北工业大学 | 2023-04-04 | — | — | CN | disclosed |