Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31438646 | 1.00 | ACHE (0.38) | ACHEALDH1A1L3MBTL1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL2409655 | 1.00 | ACHE (0.38) | ACHEALDH1A1L3MBTL1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL4006098 | 0.88 | ACHE (0.33) | ACHEALDH1A1L3MBTL1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL6542389 | 0.88 | LMNA (0.39) | ACHEALDH1A1L3MBTL1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL19272425 | 0.87 | CYP1A2 (0.36) | KLK1KLK5CA2TSHRLMNA | |
| Trifluoroacetic Acid SCHEMBL2344616 | 0.87 | FAAH (0.38) | F2F11PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL29019097 | 0.87 | TP53 (0.35) | ALDH1A1F2F11PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL3906649 | 0.86 | ALDH1A1 (0.46) | ACHEALDH1A1L3MBTL1LDHALDHB | |
| Trifluoroacetic Acid SCHEMBL934980 | 0.86 | ACHE (0.54) | ACHEALDH1A1L3MBTL1LDHALDHB | |
| Trifluoroacetic Acid SCHEMBL15533970 | 0.86 | ACHE (0.54) | ACHEALDH1A1L3MBTL1LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097957-A1 | Fluorinated thermoplastic elastomers | Daikin Industries, Limited (JP) | 2001-05-09 | — | — | EP | disclosed |