Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 11/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 11/20 | 0.38 |
| ▸ | ITGAL | P20701 | 11/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978554 | 0.89 | ITGB2 (0.41) | ITGB2ICAM1ITGALEGLN1 | |
| SCHEMBL23979038 | 0.89 | ITGB2 (0.41) | ITGB2ICAM1ITGALEGLN1 | |
| SCHEMBL26478217 | 0.86 | ITGB2 (0.37) | ITGB2ICAM1ITGALEGLN1L3MBTL1 | |
| SCHEMBL26506154 | 0.84 | ITGB2 (0.35) | ITGB2ICAM1ITGALEGLN1L3MBTL1 | |
| SCHEMBL24804783 | 0.84 | LMNA (0.38) | ITGB2ICAM1ITGALEGLN1L3MBTL1 | |
| SCHEMBL23978842 | 0.84 | LMNA (0.38) | ITGB2ICAM1ITGALEGLN1L3MBTL1 | |
| SCHEMBL30336855 | 0.83 | ITGB2 (0.40) | TSHRITGB2ICAM1ITGALEGLN1 | |
| SCHEMBL24804269 | 0.83 | EGLN1 (0.40) | EGLN1SCDL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL23979035 | 0.83 | ITGB2 (0.45) | ITGB2ICAM1ITGAL | |
| SCHEMBL30279298 | 0.83 | ITGB2 (0.45) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |