Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.40 |
| ▸ | ITGAL | P20701 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279391 | 0.85 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2L3MBTL1NCOA3EGLN1 | |
| SCHEMBL23978742 | 0.85 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2L3MBTL1NCOA3EGLN1 | |
| SCHEMBL23978844 | 0.84 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2L3MBTL1NCOA3LIPG | |
| SCHEMBL30279442 | 0.84 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2L3MBTL1NCOA3EGLN1 | |
| SCHEMBL23978743 | 0.84 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2L3MBTL1NCOA3EGLN1 | |
| SCHEMBL29019155 | 0.83 | TSHR (0.38) | ITGB2ICAM1ITGALLMNASMN1; SMN2 | |
| SCHEMBL23979038 | 0.83 | ITGB2 (0.41) | ITGB2ICAM1ITGALEGLN1 | |
| SCHEMBL23978554 | 0.83 | ITGB2 (0.41) | ITGB2ICAM1ITGALEGLN1 | |
| SCHEMBL26478217 | 0.81 | ITGB2 (0.37) | ITGB2ICAM1ITGALLMNASMN1; SMN2 | |
| SCHEMBL26506199 | 0.80 | EGLN1 (0.38) | LMNASMN1; SMN2L3MBTL1NCOA3EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |