Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.36 |
| ▸ | ITGAV | P06756 | 7/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.36 |
| ▸ | ITGAL | P20701 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083853 | 0.90 | SLC6A9 (0.35) | SLC6A9ALDH1A1 | |
| SCHEMBL24803374 | 0.90 | SLC6A9 (0.35) | SLC6A9ALDH1A1 | |
| SCHEMBL23978717 | 0.90 | SLC6A9 (0.35) | SLC6A9ALDH1A1 | |
| SCHEMBL29019164 | 0.88 | ITGB1 (0.34) | SLC6A9ITGB1ITGAVITGA4ITGA5 | |
| SCHEMBL23978569 | 0.85 | EPHX2 (0.46) | ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL23978988 | 0.85 | EPHX2 (0.46) | ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL30279441 | 0.85 | EPHX2 (0.46) | ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL26104441 | 0.85 | EPHX2 (0.46) | ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL23978637 | 0.82 | SIGMAR1 (0.37) | ITGB1ITGAVITGA4ITGA5ITGB2 | |
| SCHEMBL24803234 | 0.82 | SIGMAR1 (0.37) | ITGB1ITGAVITGA4ITGA5ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |