Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498258 | 0.71 | LRRK2 (0.40) | KDM4EIKBKBALDH1A1KMT2AGRM5 | |
| SCHEMBL5669674 | 0.69 | TGFBR1 (0.50) | KDM4EIKBKBALDH1A1KMT2AHDAC3 | |
| SCHEMBL1844025 | 0.68 | ADORA3 (0.54) | KDM4EALDH1A1KMT2ANPC1MAPT | |
| SCHEMBL30839442 | 0.68 | KDM4E (0.62) | KDM4EALDH1A1KMT2ANPC1MAPT | |
| SCHEMBL4705063 | 0.66 | GRM4 (0.48) | KDM4EALDH1A1KMT2AGRM5NPC1 | |
| SCHEMBL29177459 | 0.66 | CYP1A2 (0.51) | KMT2ANPC1MAPTRAB9A | |
| SCHEMBL2815367 | 0.66 | NPSR1 (0.47) | KDM4EIKBKBALDH1A1KMT2AGRM5 | |
| SCHEMBL3620548 | 0.65 | GRM5 (0.51) | KDM4EALDH1A1GRM5NPC1MAPT | |
| SCHEMBL2465495 | 0.65 | KDM4E (0.45) | KDM4EALDH1A1GRM5NPC1RAB9A | |
| SCHEMBL29988036 | 0.65 | KDM4E (0.45) | KDM4EALDH1A1GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096725-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2023-05-09 | — | — | CN | disclosed |