Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.35 |
| ▸ | HPGD | P15428 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.34 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971846 | 0.75 | GABRA1 (0.44) | ALDH1A1HSD17B10HPGDPIK3CDPIK3R2 | |
| SCHEMBL15867016 | 0.75 | GABRA1 (0.41) | ALDH1A1HSD17B10HPGDPIK3CDPIK3R2 | |
| SCHEMBL29871089 | 0.75 | GABRA1 (0.44) | ALDH1A1HSD17B10HPGDPIK3CDPIK3R2 | |
| Hydrochloric Acid SCHEMBL30337257 | 0.74 | GABRA1 (0.43) | ALDH1A1HSD17B10HPGDPIK3CDPIK3R2 | |
| SCHEMBL29830882 | 0.71 | OGA (0.35) | ALDH1A1HSD17B10HPGDTSHRUSP2 | |
| SCHEMBL30337063 | 0.71 | CD274 (0.40) | ALDH1A1HSD17B10PIK3CDPIK3R2PIK3CA | |
| SCHEMBL31483731 | 0.70 | GRM7 (0.50) | ALDH1A1HSD17B10HPGDSMN1; SMN2CRBN | |
| SCHEMBL20836367 | 0.70 | GRM7 (0.50) | ALDH1A1HSD17B10HPGDSMN1; SMN2CRBN | |
| SCHEMBL23648620 | 0.69 | PLD1 (0.41) | ALDH1A1HSD17B10HPGDTSHRUSP2 | |
| SCHEMBL29870923 | 0.69 | PLD1 (0.41) | ALDH1A1HSD17B10HPGDTSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156379-A | Novel pyrazole derivatives | 阿普塔生物治疗公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-115916766-A | Novel pyrazole derivatives | 阿普塔生物治疗公司 | 2023-04-04 | — | — | CN | disclosed |