Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15867016 | 0.80 | GABRA1 (0.41) | CCNA2CDK2CCNA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29871089 | 0.80 | GABRA1 (0.44) | CCNA2CDK2CCNA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4971846 | 0.80 | GABRA1 (0.44) | CCNA2CDK2CCNA1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30337257 | 0.79 | GABRA1 (0.43) | CCNA2CDK2CCNA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23648620 | 0.73 | PLD1 (0.41) | CCNA2CDK2CCNA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29870923 | 0.73 | PLD1 (0.41) | CCNA2CDK2CCNA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28818366 | 0.72 | P2RX7 (0.41) | SMN1; SMN2ALDH1A1HSD17B10PIK3CDPIK3R2 | |
| SCHEMBL23648633 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL29019285 | 0.71 | ALDH1A1 (0.35) | CCNA2CDK2CCNA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23648784 | 0.71 | ALDH1A1 (0.45) | CCNA2CDK2CCNA1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156379-A | Novel pyrazole derivatives | 阿普塔生物治疗公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-115916766-A | Novel pyrazole derivatives | 阿普塔生物治疗公司 | 2023-04-04 | — | — | CN | disclosed |