Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30046979 | 0.76 | AKR1C2 (0.44) | AKR1C2AKR1C1AURKATPX2MAPT | |
| SCHEMBL28056213 | 0.71 | AKR1C2 (0.45) | AKR1C2AKR1C1AURKATPX2MAPT | |
| SCHEMBL966803 | 0.71 | AKR1C2 (0.45) | AKR1C2AKR1C1AURKATPX2MAPT | |
| SCHEMBL30366911 | 0.69 | KIF11 (0.40) | AURKATPX2MAPTSCN5ATRPV1 | |
| SCHEMBL28716842 | 0.68 | MAOB (0.41) | AURKATPX2MAPTSCN5AMAPK1 | |
| SCHEMBL508237 | 0.68 | AURKA (0.57) | AKR1C2AKR1C1AURKATPX2MAPT | |
| SCHEMBL23041015 | 0.67 | KIF11 (0.41) | AKR1C2AKR1C1AURKATPX2SCN5A | |
| SCHEMBL30046652 | 0.67 | KIF11 (0.41) | SCN5AL3MBTL1 | |
| SCHEMBL8470711 | 0.67 | MEN1 (0.49) | AURKATPX2MAPTFFAR1FFAR4 | |
| SCHEMBL22816653 | 0.67 | ESR1 (0.56) | AKR1C2AKR1C1AURKATPX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |