Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966803 | 0.84 | AKR1C2 (0.45) | AKR1C2AKR1C1TSHRHSD17B10TDP1 | |
| SCHEMBL8065084 | 0.81 | GPR3 (0.48) | AKR1C2AKR1C1GPR3FFAR4FFAR1 | |
| SCHEMBL29894167 | 0.81 | GPR3 (0.48) | AKR1C2AKR1C1GPR3FFAR4FFAR1 | |
| SCHEMBL24445841 | 0.81 | GPR3 (0.48) | CYP3A4HSD17B10GPR3CYP2C9SCN5A | |
| SCHEMBL23519088 | 0.80 | AKR1C2 (0.40) | AKR1C2AKR1C1ALDH1A1CYP3A4TSHR | |
| Water SCHEMBL27776401 | 0.78 | GPR3 (0.43) | AKR1C2AKR1C1CYP3A4HSD17B10TDP1 | |
| SCHEMBL11065683 | 0.78 | FFAR4 (0.48) | AKR1C2AKR1C1CYP3A4GPR3FFAR4 | |
| SCHEMBL15959092 | 0.78 | CA3 (0.46) | GPR3FFAR4FFAR1KIF11AURKA | |
| SCHEMBL14237497 | 0.76 | GPR3 (0.44) | AKR1C2AKR1C1CYP3A4HSD17B10TDP1 | |
| SCHEMBL16957287 | 0.76 | GPR3 (0.44) | AKR1C2AKR1C1CYP3A4HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118983-A | Xanthone compound and intermediate thereof, preparation method, pharmaceutical composition and application | 上海药坦药物研究开发有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-105431427-B | Novel PDE 4 inhibitor | 明治制果药业株式会社 | 2017-12-08 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |