Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 13/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265154 | 0.83 | DHFR (0.59) | DHFRHRH4KDM4EALDH1A1GAA | |
| SCHEMBL30560046 | 0.83 | DHFR (0.59) | DHFRHRH4KDM4EALDH1A1GAA | |
| SCHEMBL29964925 | 0.78 | FYN (0.41) | DHFRKDM4EALDH1A1GAAMAPT | |
| SCHEMBL28324074 | 0.75 | DHFR (0.65) | DHFRHRH4 | |
| SCHEMBL16892046 | 0.74 | HRH4 (0.58) | HRH4HRH3KDM4EALDH1A1GAA | |
| SCHEMBL521324 | 0.73 | MAPT (0.58) | HRH4HRH3KDM4EALDH1A1GAA | |
| SCHEMBL29664444 | 0.73 | MAPT (0.58) | HRH4HRH3KDM4EALDH1A1GAA | |
| SCHEMBL20734720 | 0.72 | DHFR (0.74) | DHFR | |
| SCHEMBL24681609 | 0.71 | FYN (0.49) | HRH4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL28012682 | 0.70 | KDM4E (0.57) | DHFRHRH4HRH3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620852-B | 5-chloro-pyrimidine-2, 4-diamine compound, and preparation method and application thereof | 镇江植生源农业科技有限公司 | 2023-05-09 | — | — | CN | disclosed |