Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664444 | 1.00 | MAPT (0.58) | MAPTGAAKDM4EPTK2BADRA2C | |
| SCHEMBL2821413 | 0.93 | MAPT (0.51) | MAPTGAAKDM4EPTK2BADRA2C | |
| Pyridine SCHEMBL28293022 | 0.89 | GAA (0.47) | MAPTGAAKDM4EPTK2BADRA2C | |
| SCHEMBL28051294 | 0.86 | RPS6KA3 (0.59) | MAPTGAAKDM4EPTK2BADRA2C | |
| SCHEMBL23126541 | 0.85 | PIK3CA (0.53) | MAPTGAAKDM4EPTK2BADRA2C | |
| SCHEMBL10126764 | 0.85 | ACVR1 (0.53) | PIK3CAMTOR | |
| SCHEMBL13779836 | 0.82 | MAPT (0.50) | MAPTGAAKDM4EKMT2AALDH1A1 | |
| SCHEMBL3367822 | 0.82 | CHRNB2 (0.47) | MAPTGAAKDM4EKMT2AALDH1A1 | |
| SCHEMBL29883782 | 0.82 | MAPT (0.50) | MAPTGAAKDM4EKMT2AALDH1A1 | |
| SCHEMBL17108487 | 0.82 | DRD2 (0.54) | MAPTGAAKDM4EGFERPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 800 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903147-A | Preparation method of treasipril and intermediate thereof | 沈阳药科大学 | 2024-04-19 | — | — | CN | claimed |
| CN-113788837-B | Trilaciclib synthesis method | 深圳湾实验室坪山生物医药研发转化中心 | 2022-08-26 | — | — | CN | claimed |
| CN-114380822-A | CDKs inhibitor of beta-carboline mother nucleus, preparation method and anti-tumor application thereof | 中国人民解放军北部战区总医院 | 2022-04-22 | — | — | CN | claimed |
| CN-110157251-B | Curing agent composition and coating composition comprising same | ＫＣＣ公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113788837-A | Trilaciclib synthesis method | 深圳湾实验室坪山生物医药研发转化中心 | 2021-12-14 | — | — | CN | claimed |
| CN-106008533-A | Cdk inhibitors | G1治疗公司 | 2016-10-12 | — | — | CN | claimed |
| CN-104046246-B | The chemical-mechanical planarization of tungsten-containing substrate | 气体产品与化学公司 | 2016-06-15 | — | — | CN | claimed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | claimed |
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | claimed |
| EP-3478295-B1 | SYNTHESIS OF N-(HETEROARYL)-PYRROLO[3,2-D]PYRIMIDIN-2-AMINES | PHARMACOSMOS HOLDING AS (DK) | 2026-05-27 | — | — | EP | disclosed |
| EP-4027995-B1 | HPK1 ANTAGONISTS AND USES THEREOF | NIMBUS SATURN INC (US) | 2026-05-27 | — | — | EP | disclosed |
| CN-122010959-A | Novel synthesis method of treasipril | 上海上药第一生化药业有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12606566-B2 | Substituted cyclopenta[4,5]pyrrolo[1,2-a]pyrazines as bruton's tyrosine kinase inhibitors | SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD. (CN) | 2026-04-21 | — | — | US | disclosed |
| US-12595236-B2 | Pyrimidine-2,4-diamine compound and preparation method and application thereof | ANHUI MEDICAL UNIVERSITY (CN) | 2026-04-07 | — | — | US | disclosed |
| US-20050038078-A1 | Antiproliferative 2-(heteroaryl)-aminothiazole compounds and pharmaceutical compositions, and methods for their use | AGOURON PHARMACEUTICALS, INC. | 2005-02-17 | — | — | US | disclosed |
| EP-1470124-A1 | 2-(PYRIDIN-2-YLAMINO)-PYRIDO 2,3-d]PYRIMIDIN-7-ONES | Warner-Lambert Company LLC (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2004014904-A1 | ANTIPROLIFERATIVE 2-(HETEROARYL)-AMINOTHIAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE | PFIZER INC. (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20030149001-A1 | 2-(Pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones | BARVIAN MARK (US) | 2003-08-07 | — | — | US | disclosed |
| WO-2003062236-A1 | 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d]PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY LLC (US) | 2003-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149001-A1 | 2-(Pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones | CDK4, CDK2, CDK1 | MAPT 3765/4885GAA 3493/4885KDM4E 542/4885 |
| US-12606566-B2 | Substituted cyclopenta[4,5]pyrrolo[1,2-a]pyrazines as bruton's tyrosine kinase inhibitors | BTK, LYN, SYK | MAPT 3697/4885GAA 4455/4885KDM4E 1713/4885 |
| US-20050038078-A1 | Antiproliferative 2-(heteroaryl)-aminothiazole compounds and pharmaceutical compositions, and methods for their use | CDK2, CCNK, MKI67 | MAPT 2107/4885GAA 1197/4885KDM4E 2190/4885 |
| US-12595236-B2 | Pyrimidine-2,4-diamine compound and preparation method and application thereof | CTSZ, CTSV, CASP2 | MAPT 3995/4885GAA 736/4885KDM4E 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.