SCHEMBL29020276

SCHEMBL29020276

O=C(Cc1cccc(F)c1)Oc1ccc[nH]1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP12 P39900 1/20 0.39
NR4A2 P43354 2/20 0.39
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39
HCAR2 Q8TDS4 2/20 0.39
DAO P14920 1/20 0.39
IDO1 P14902 2/20 0.38
AGXT P21549 2/20 0.38
MAOB P27338 3/20 0.38
PARP10 Q53GL7 1/20 0.38
ALDH1A1 P00352 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CASP3 P42574 1/20 0.37
CASP7 P55210 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29020283 0.84 KMT2A (0.49) ALDH1A1MAPK1HSD17B10
SCHEMBL29020256 0.83 EGFR (0.40) MMP1MMP2MMP9MMP12HCAR2
SCHEMBL29020273 0.83 CTBP2 (0.44) MMP2MMP9MMP12DAOIDO1
SCHEMBL29020262 0.83 CTBP2 (0.46) MMP1MMP2MMP9MMP12NR4A2
SCHEMBL29020257 0.82 SMN1; SMN2 (0.50) ALDH1A1MAPK1
SCHEMBL29225324 0.78 ALDH1A1 (0.43) MMP1MMP2MMP9MMP12NR4A2
SCHEMBL17674564 0.76 CYP19A1 (0.55) NR4A2PPARGPPARAMAOBALDH1A1
SCHEMBL31225718 0.76 SMN1; SMN2 (0.51) NR4A2HCAR2IDO1AGXTMAOB
SCHEMBL29020249 0.75 L3MBTL1 (0.46) ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL29020270 0.75 SMN1; SMN2 (0.40) PPARGPPARAALDH1A1ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093355-A Preparation method of pyrrole ester compound 河南农业大学 2022-09-23 CN disclosed