Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutanol SCHEMBL1004229 | 0.88 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNATHRB | |
| SCHEMBL789937 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL28578 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL15864609 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL55583 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL7522896 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL161401 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL3535 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| SCHEMBL2107487 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323726-A | Active energy ray-curable composition, cured product, lens, and camera module | DIC株式会社 | 2023-06-23 | — | — | CN | disclosed |