Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.58 |
| ▸ | METAP2 | P50579 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29020514 | 0.92 | CYP3A4 (0.53) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL29020512 | 0.91 | CYP3A4 (0.57) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL30498867 | 0.88 | METAP2 (0.52) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL29020511 | 0.88 | METAP2 (0.52) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL29020560 | 0.83 | PTK2 (0.54) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL6404838 | 0.80 | CYP3A4 (0.78) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL28376474 | 0.76 | MAPK1 (0.54) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL16486457 | 0.75 | PTK2 (0.61) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL28372567 | 0.74 | SMN1; SMN2 (0.53) | TERTMETAP2PTGS2MEN1KMT2A | |
| SCHEMBL28376596 | 0.73 | MEN1 (0.55) | TERTMETAP2MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402473-B | Thiotriazole compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2023-06-23 | — | — | CN | disclosed |
| CN-113402473-A | Thiotriazole compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2021-09-17 | — | — | CN | disclosed |