Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TERT | O14746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404838 | 0.87 | CYP3A4 (0.78) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL16486196 | 0.78 | SMN1; SMN2 (0.69) | KMT2AMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL6410759 | 0.78 | CYP3A4 (0.83) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL6402486 | 0.76 | CYP3A4 (0.72) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL6408279 | 0.76 | CYP3A4 (0.80) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL6408014 | 0.75 | CYP3A4 (0.71) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL6403463 | 0.75 | CYP3A4 (0.73) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL29020535 | 0.75 | TERT (0.58) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL29020511 | 0.72 | METAP2 (0.52) | PTK2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL30498867 | 0.72 | METAP2 (0.52) | PTK2CYP3A4CYP2C9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021943-A9 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015021943-A1 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-19 | — | — | WO | disclosed |