Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14154124 | 0.91 | HCRTR2 (0.35) | APPEPHX2 | |
| SCHEMBL11572946 | 0.88 | NPC1 (0.40) | APP | |
| SCHEMBL18775629 | 0.78 | NPC1 (0.41) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL18775641 | 0.77 | NPC1 (0.44) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL22162622 | 0.76 | APP (0.31) | APP | |
| SCHEMBL421993 | 0.76 | APP (0.50) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL22162619 | 0.75 | — | — | |
| SCHEMBL25299218 | 0.74 | APP (0.48) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL20875302 | 0.74 | APP (0.48) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL19640302 | 0.74 | APP (0.48) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115919859-A | Pharmaceutical composition of heteroaryl derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-07 | — | — | CN | disclosed |