Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24207600 | 0.86 | FFAR4 (0.45) | — | |
| SCHEMBL25339547 | 0.84 | NOTUM (0.44) | F10 | |
| SCHEMBL25339552 | 0.84 | NOTUM (0.44) | F10 | |
| SCHEMBL29021196 | 0.84 | ALDH1A1 (0.41) | GRM5GRM3 | |
| SCHEMBL24206805 | 0.83 | FFAR4 (0.42) | — | |
| SCHEMBL24207014 | 0.83 | CHRM4 (0.38) | LRRK2 | |
| SCHEMBL31143335 | 0.83 | ACACB (0.37) | GRM5ACACB | |
| SCHEMBL28899818 | 0.83 | LTA4H (0.39) | GRM5F10ACACB | |
| SCHEMBL25957189 | 0.83 | LTA4H (0.39) | GRM5F10ACACB | |
| SCHEMBL30511792 | 0.83 | MYC (0.38) | GRM5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323580-A | Conjugated degradation (EGFR) of EGFR inhibitors to E3 ligase ligands and methods of use | 百济神州有限公司 | 2023-06-23 | — | — | CN | disclosed |