Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022352 | 0.74 | USP2 (0.38) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL29022350 | 0.74 | USP2 (0.38) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL29022331 | 0.73 | USP2 (0.40) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL29679482 | 0.73 | GPR119 (0.46) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL27649003 | 0.73 | USP2 (0.40) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL29022329 | 0.73 | USP2 (0.40) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL29022286 | 0.72 | ALDH1A1 (0.40) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL29022283 | 0.72 | ALDH1A1 (0.40) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL31646266 | 0.72 | USP2 (0.39) | USP2SMN1; SMN2ALDH1A1MALT1TSHR | |
| SCHEMBL29022271 | 0.72 | USP2 (0.39) | USP2SMN1; SMN2ALDH1A1MALT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793409-B | Dihydropyrimidine compound and application thereof in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |