Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905115 | 0.79 | HTR2C (0.52) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL4058433 | 0.76 | ALDH1A1 (0.50) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL10797345 | 0.76 | ALDH1A1 (0.53) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL1188627 | 0.75 | HTR2C (0.56) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL1188626 | 0.75 | HTR2C (0.56) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL1188628 | 0.75 | HTR2C (0.56) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL23124030 | 0.74 | HTR2C (0.43) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL29849418 | 0.74 | CHRM1 (0.60) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL30524578 | 0.74 | CHRM1 (0.60) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL5517077 | 0.73 | HTR2C (0.64) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217226-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009061879-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |