Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RARB | P10826 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642541 | 1.00 | TP53 (0.63) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL9221274 | 1.00 | TP53 (0.63) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL79521 | 0.84 | TP53 (0.70) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL9670519 | 0.84 | TP53 (0.70) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL8081129 | 0.84 | TP53 (0.65) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL8081520 | 0.84 | TP53 (0.65) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL8081503 | 0.84 | TP53 (0.65) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL8072237 | 0.84 | TP53 (0.65) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL55063 | 0.84 | TP53 (0.65) | TP53TSHRPLA2G4BNR5A1LMNA | |
| SCHEMBL9670514 | 0.84 | TP53 (0.65) | TP53TSHRPLA2G4BNR5A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109021-B | Synthesis of N- (4-alkoxyphenyl) -7-methoxycoumarin-3-carboxamide, gel prepared by same and application thereof | 天津大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-115109021-A | Synthesis of N- (4-alkoxy phenyl) -7-methoxy coumarin-3-formamide, gel prepared from N- (4-alkoxy phenyl) -7-methoxy coumarin-3-formamide and application of gel | 天津大学 | 2022-09-27 | — | — | CN | disclosed |