Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Dexborneol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Borneol SCHEMBL29022976 | 1.00 | KMT2A (0.47) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL31540151 | 0.94 | KMT2A (0.50) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL31454019 | 0.94 | KMT2A (0.50) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Borneol SCHEMBL28250992 | 0.87 | CA2 (0.46) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Dexborneol SCHEMBL28250994 | 0.87 | CA2 (0.46) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Dexborneol SCHEMBL28706552 | 0.86 | KMT2A (0.50) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Phthalic Acid SCHEMBL27666788 | 0.86 | KMT2A (0.45) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Dexborneol SCHEMBL29187751 | 0.86 | ALDH1A1 (0.51) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Borneol SCHEMBL29187750 | 0.86 | ALDH1A1 (0.51) | KMT2AMEN1CYP2C19HTTSMN1; SMN2 | |
| Borneol SCHEMBL28793592 | 0.85 | CA1 (0.51) | KMT2AMEN1CYP2C19SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116207344-B | Flame-retardant polyurethane acrylate solid electrolyte membrane and preparation method and application thereof | 武汉工程大学 | 2026-02-27 | — | — | CN | claimed |
| CN-116440116-A | Nanometer medicine with antibacterial function and application thereof | 北京化工大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116207344-A | Flame-retardant polyurethane acrylate solid electrolyte membrane and preparation method and application thereof | 武汉工程大学 | 2023-06-02 | — | — | CN | claimed |
| CN-117753230-A | preparation method of borneol ester-containing conjugated microporous polymer/MXene chiral composite membrane | 齐齐哈尔大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116440116-A | Nanometer medicine with antibacterial function and application thereof | 北京化工大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-110354113-B | Borneol derivative antibacterial agent and preparation method and application thereof | 北京化工大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-110354113-B | Borneol derivative antibacterial agent and preparation method and application thereof | 北京化工大学 | 2023-05-26 | — | — | CN | disclosed |