Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299428 | 1.00 | KDM4E (0.59) | KDM4EMAPTLMNATSHRHPGD | |
| SCHEMBL29023338 | 0.88 | TSHR (0.52) | KDM4EMAPTLMNATSHRHPGD | |
| SCHEMBL29023330 | 0.88 | KDM4E (0.50) | KDM4EMAPTLMNATSHRALOX15 | |
| SCHEMBL30299422 | 0.88 | LMNA (0.52) | KDM4EMAPTLMNATSHRHPGD | |
| SCHEMBL30299415 | 0.88 | KDM4E (0.50) | KDM4EMAPTLMNATSHRALOX15 | |
| SCHEMBL30299419 | 0.88 | L3MBTL1 (0.49) | KDM4EMAPTLMNATSHRGAA | |
| SCHEMBL30299420 | 0.88 | TSHR (0.52) | KDM4EMAPTLMNATSHRHPGD | |
| SCHEMBL29023336 | 0.88 | LMNA (0.52) | KDM4EMAPTLMNATSHRHPGD | |
| SCHEMBL29023332 | 0.88 | L3MBTL1 (0.49) | KDM4EMAPTLMNATSHRGAA | |
| SCHEMBL29023331 | 0.84 | MAPT (0.55) | KDM4EMAPTLMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879840-B | 4-piperazinemethyl-7-hydroxybenzofuran compound and medical application thereof | 沈阳大学 | 2023-04-11 | — | — | CN | disclosed |