Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25383667 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNASIRT6HTTKMT2A | |
| SCHEMBL2946935 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNASIRT6HTTKMT2A | |
| SCHEMBL1230074 | 0.70 | ALDH1A1 (0.77) | ALDH1A1LMNASIRT6HTTKMT2A | |
| SCHEMBL25383409 | 0.70 | ALDH1A1 (0.45) | ALDH1A1LMNASIRT6HTTKMT2A | |
| SCHEMBL3705317 | 0.70 | MAPT (0.63) | ALDH1A1LMNAKMT2AMAPTNPC1 | |
| SCHEMBL29788525 | 0.69 | HTT (0.59) | ALDH1A1LMNAHTTKMT2AMAPT | |
| SCHEMBL23144086 | 0.69 | ALDH1A1 (0.51) | ALDH1A1LMNASIRT6KMT2AMAPT | |
| SCHEMBL29811691 | 0.69 | ALDH1A1 (0.51) | ALDH1A1LMNASIRT6KMT2AMAPT | |
| SCHEMBL12312133 | 0.68 | TMEM97 (0.54) | ALDH1A1LMNAHTTKMT2AMAPT | |
| SCHEMBL3698388 | 0.68 | NPC1 (0.55) | ALDH1A1LMNASIRT6HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114426542-B | Substituted diarylamine compounds, pharmaceutical compositions, preparation method and use thereof | 苏州亚宝药物研发有限公司 | 2023-06-30 | — | — | CN | disclosed |