SCHEMBL29023915

SCHEMBL29023915

CCCCCCCCCCCCc1ccc(C(=O)O)c(-c2ccc(O)cc2)c1-c1ccc(C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.47
PPARA Q07869 2/20 0.45
RARA P10276 1/20 0.44
RARG P13631 1/20 0.44
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX5 P09917 1/20 0.43
MAPT P10636 1/20 0.43
TYR P14679 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PLK1 P53350 4/20 0.43
KAT8 Q9H7Z6 4/20 0.42
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4965468 0.82 HTT (0.44) MEN1TP53CYP3A4ALOX5MAPT
SCHEMBL28360757 0.78 GABRP (0.43) RARBPPARARARARARGMEN1
SCHEMBL11323683 0.78 RARB (0.49) RARBPPARARARARARGPLK1
SCHEMBL11811033 0.77 RARB (0.69) RARBPPARARARARARGMEN1
SCHEMBL3275839 0.77 RARB (0.69) RARBPPARARARARARGMEN1
SCHEMBL11520153 0.75 RARB (0.67) RARBPPARARARARARGMEN1
SCHEMBL811763 0.74 PPARA (0.59) RARBPPARARARARARGMEN1
SCHEMBL2811080 0.74 PLK1 (0.58) RARBPPARARARARARGPLK1
SCHEMBL2802711 0.74 PPARA (0.59) RARBPPARARARARARGMEN1
SCHEMBL290916 0.74 PPARA (0.59) RARBPPARARARARARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116390974-A Light stabilizer master batch and method for producing polypropylene resin composition using same 株式会社艾迪科 2023-07-04 CN disclosed
CN-116323792-A Polyolefin resin composition, molded article using same, and method for producing polyolefin resin composition 株式会社艾迪科 2023-06-23 CN disclosed
CN-116323782-A Polyolefin resin composition, molded article using same, and method for producing polyolefin resin composition 株式会社艾迪科 2023-06-23 CN disclosed