Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402301 | 1.00 | MAPK1 (0.40) | MAPK1TSHRSLC6A4HTR2CHTR2B | |
| SCHEMBL25889282 | 1.00 | MAPK1 (0.40) | MAPK1TSHRSLC6A4HTR2CHTR2B | |
| SCHEMBL25298519 | 0.87 | TDP1 (0.40) | SLC6A4SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL25256796 | 0.87 | TDP1 (0.40) | SLC6A4SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL18582829 | 0.86 | LRRK2 (0.42) | MAPK1SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL18582827 | 0.86 | LRRK2 (0.42) | MAPK1SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL29509060 | 0.80 | PDK1 (0.47) | MAPK1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7481571 | 0.80 | PDK1 (0.47) | MAPK1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24133484 | 0.76 | SLC6A4 (0.43) | SLC6A4HTR2CHTR2BHTR6SMN1; SMN2 | |
| SCHEMBL31402228 | 0.76 | SLC6A4 (0.43) | SLC6A4HTR2CHTR2BHTR6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956070-A | Sulfonamide compounds | 阿纳克西斯制药股份有限公司 | 2023-04-11 | — | — | CN | disclosed |