SCHEMBL25889282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31402301	1.00	MAPK1 (0.40)	MAPK1TSHRSLC6A4HTR2CHTR2B
	SCHEMBL29024322	1.00	MAPK1 (0.40)	MAPK1TSHRSLC6A4HTR2CHTR2B
	SCHEMBL25298519	0.87	TDP1 (0.40)	SLC6A4SMN1; SMN2ALDH1A1LMNAMAPT
	SCHEMBL25256796	0.87	TDP1 (0.40)	SLC6A4SMN1; SMN2ALDH1A1LMNAMAPT
	SCHEMBL18582829	0.86	LRRK2 (0.42)	MAPK1SLC6A4HTR2CHTR2BHTR6
	SCHEMBL18582827	0.86	LRRK2 (0.42)	MAPK1SLC6A4HTR2CHTR2BHTR6
	SCHEMBL29509060	0.80	PDK1 (0.47)	MAPK1TSHRSMN1; SMN2ALDH1A1LMNA
	SCHEMBL7481571	0.80	PDK1 (0.47)	MAPK1TSHRSMN1; SMN2ALDH1A1LMNA
	SCHEMBL24133484	0.76	SLC6A4 (0.43)	SLC6A4HTR2CHTR2BHTR6SMN1; SMN2
	SCHEMBL31402228	0.76	SLC6A4 (0.43)	SLC6A4HTR2CHTR2BHTR6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.