Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644653 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL56884 | 0.80 | CYP2A6 (1.00) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL27556684 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL29629031 | 0.80 | CYP2A6 (1.00) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL1567214 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL7416778 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL8996544 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL7079637 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL1567141 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C | |
| SCHEMBL12884253 | 0.80 | CYP2A6 (0.64) | CYP2A6GSK3BTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-A | Cyanotriazole compounds | OTSUKA PHARMA CO LTD | 2016-03-16 | — | — | CN | claimed |
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |
| EP-2759543-B1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| EP-2725017-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2016-06-29 | — | — | EP | disclosed |
| CN-105408325-A | Cyanotriazole compounds | OTSUKA PHARMA CO LTD | 2016-03-16 | — | — | CN | disclosed |
| EP-2669277-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-07-01 | — | — | EP | disclosed |
| EP-2684886-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-06-03 | — | — | EP | disclosed |
| EP-2669278-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-05-27 | — | — | EP | disclosed |
| US-8916071-B2 | Chromene compound and curable composition | TOKUYAMA CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-1655293-A2 | Chromene compound | Tokuyama Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
| CN-1590357-A | Lightfast additive having uv-absorbing moiety and ink composition including the same | SAMSUNG ELECTRONICS CO LTD (KR) | 2005-03-09 | — | — | CN | disclosed |
| US-20040237837-A1 | Lightfast additive having UV-absorbing moiety and ink composition including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2004-12-02 | — | — | US | disclosed |
| US-6723859-B2 | BASE STRUCTURE IS A CHROMENE(3,2-A)FLUORENE RING CONTAINING SPIRO-FUSED RINGS; PHOTOCHROMIC LENSES; LARGE FADING RATE, LESS COLOR WHEN DETERIORATED, AND EXCELLENT LIGHT RESISTANCE IN THE PHOTOCHROMIC PROPERTIES | TOKUYAMA CORPORATION (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20040014995-A1 | Chromene compounds | KAWABATA YUICHIRO (JP) | 2004-01-22 | — | — | US | disclosed |
| US-20030096117-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2003-05-22 | — | — | US | disclosed |
| US-6469076-B1 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6384065-B1 | CONTROL THE FUNCTIONS OF PROTEINS SUCH AS ENZYMES AND RECEPTOR FORTREATING INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS, | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1184379-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-1116723-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237837-A1 | Lightfast additive having UV-absorbing moiety and ink composition including the same | CDK4, CDKL4, UGT1A4 | CYP2A6 1337/4885GSK3B 4140/4885TUBB4A 737/4885 |
| US-20040014995-A1 | Chromene compounds | SMARCE1, SMARCB1, SMARCA2 | CYP2A6 2241/4885GSK3B 2854/4885TUBB4A 3251/4885 |
| US-20030096117-A1 | Chromene compound | SMARCE1, SMARCD2, SMARCB1 | CYP2A6 2342/4885GSK3B 2866/4885TUBB4A 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.