SCHEMBL8996544

SCHEMBL8996544

N=Cc1cc2ccccc2s1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.64
GSK3B P49841 1/20 0.46
TUBB4A P04350 2/20 0.45
TUBB P07437 2/20 0.45
TUBA3C P0DPH7 2/20 0.45
TUBA1B P68363 2/20 0.45
TUBA4A P68366 2/20 0.45
TUBB4B P68371 2/20 0.45
TUBB3 Q13509 2/20 0.45
TUBB2A Q13885 2/20 0.45
TUBB8 Q3ZCM7 2/20 0.45
TUBA3E Q6PEY2 2/20 0.45
TUBA1A Q71U36 2/20 0.45
TUBA1C Q9BQE3 2/20 0.45
TUBB6 Q9BUF5 2/20 0.45
TUBB2B Q9BVA1 2/20 0.45
TUBB1 Q9H4B7 2/20 0.45
ASIC3 Q9UHC3 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
MGLL Q99685 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2902480 0.80 CYP2A6 (0.67) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL1567141 0.78 CYP2A6 (0.64) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL12884253 0.78 CYP2A6 (0.64) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL27556684 0.78 CYP2A6 (0.64) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL7079637 0.78 CYP2A6 (0.64) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL7416778 0.78 CYP2A6 (0.64) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL1567214 0.78 CYP2A6 (0.64) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL29629031 0.78 CYP2A6 (1.00) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL56884 0.78 CYP2A6 (1.00) CYP2A6GSK3BTUBB4ATUBBTUBA3C
SCHEMBL27645156 0.78 CYP2A6 (0.64) CYP2A6GSK3BTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5547980-A ANTIALLERGENS, BRONCHODILATOR BOEHRINGER MANNHEIM GMBH (DE) 1996-08-20 US disclosed