Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464792 | 0.91 | CNR2 (0.44) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL2467398 | 0.90 | CNR2 (0.46) | NPC1RAB9ALMNAPOLBCNR1 | |
| SCHEMBL8204058 | 0.85 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL29813370 | 0.83 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL108807 | 0.83 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL7588136 | 0.81 | CNR1 (0.44) | NPC1RAB9ALMNAPOLBCNR1 | |
| SCHEMBL673359 | 0.80 | CNR1 (0.40) | NPC1RAB9ALMNAPOLBCNR1 | |
| SCHEMBL8861285 | 0.80 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL139856 | 0.79 | CNR1 (0.47) | NPC1RAB9ALMNAPOLBCNR1 | |
| SCHEMBL22289027 | 0.79 | CNR1 (0.42) | NPC1RAB9ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113614138-B | Two-component polyurethane coating with improved pot life without loss of weatherability | 科思创知识产权两合公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-111344328-B | Method for manufacturing an article and use of a free radical crosslinkable resin in an additive manufacturing process | 科思创德国股份有限公司 | 2023-05-30 | — | — | CN | disclosed |