Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291861 | 0.82 | TDP1 (0.47) | GAAALDH1A1LMNACYP1A2MAPK1 | |
| SCHEMBL9629064 | 0.80 | GAA (0.84) | GAAALDH1A1PHLPP2LMNACYP1A2 | |
| SCHEMBL23581372 | 0.79 | CES2 (0.47) | GAALMNACYP1A2MAPK1RAB9A | |
| SCHEMBL4526065 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNACYP1A2MAPK1KDM4E | |
| SCHEMBL14218218 | 0.78 | GAA (0.66) | GAAALDH1A1PHLPP2LMNACYP1A2 | |
| SCHEMBL14218448 | 0.78 | GAA (0.66) | GAAALDH1A1PHLPP2LMNACYP1A2 | |
| SCHEMBL14218445 | 0.78 | PHLPP2 (0.79) | GAAALDH1A1PHLPP2LMNACYP1A2 | |
| SCHEMBL29024895 | 0.78 | GAA (0.51) | GAAALDH1A1PHLPP2LMNACYP1A2 | |
| SCHEMBL8055450 | 0.77 | TDP1 (0.73) | GAAALDH1A1PHLPP2LMNACYP1A2 | |
| SCHEMBL17672462 | 0.77 | PHLPP2 (0.56) | GAAALDH1A1PHLPP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354993-A | Reactive Oxygen Species (ROS) responsive cations and their use in siRNA delivery | 中国科学院合肥物质科学研究院 | 2023-06-30 | — | — | CN | disclosed |