Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503654 | 1.00 | NPC1 (0.57) | NPC1RAB9ABAZ1AMAPTMEN1 | |
| SCHEMBL29024742 | 0.83 | NPC1 (0.64) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30503637 | 0.83 | NPC1 (0.64) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL29024932 | 0.81 | NPC1 (0.80) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30503661 | 0.81 | NPC1 (0.80) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL5657895 | 0.81 | NPC1 (0.74) | NPC1RAB9ABAZ1AMAPTMEN1 | |
| SCHEMBL29024930 | 0.79 | MEN1 (0.58) | NPC1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL29024921 | 0.79 | MAPT (0.60) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30503668 | 0.79 | NPC1 (0.71) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL29024918 | 0.79 | NPC1 (0.71) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354879-A | Benzamide derivative and application thereof | 中国药科大学 | 2023-06-30 | — | — | CN | disclosed |