Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024921 | 0.82 | MAPT (0.60) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL29024929 | 0.79 | NPC1 (0.57) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL30503654 | 0.79 | NPC1 (0.57) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL17699318 | 0.72 | KMT2A (0.74) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL24460423 | 0.72 | KMT2A (0.63) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL391334 | 0.72 | L3MBTL1 (0.62) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL29448257 | 0.72 | L3MBTL1 (0.62) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL12133505 | 0.71 | PDGFRB (0.61) | MEN1KMT2AMAPTNPC1PLAU | |
| SCHEMBL25353807 | 0.70 | KMT2A (0.60) | MEN1KMT2AMAPTNPC1HSP90AA1 | |
| SCHEMBL10466162 | 0.70 | HTT (0.67) | MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354879-A | Benzamide derivative and application thereof | 中国药科大学 | 2023-06-30 | — | — | CN | disclosed |