Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18894018 | 0.86 | ALOX5 (0.45) | CYP3A4HSD17B10ALDH1A1TTRTSHR | |
| SCHEMBL22119888 | 0.86 | CYP3A4 (0.46) | CYP3A4HSD17B10ALDH1A1TTRTSHR | |
| SCHEMBL4376307 | 0.80 | ERN1 (0.58) | ALDH1A1 | |
| SCHEMBL28173580 | 0.80 | CA1 (0.37) | CYP3A4ALDH1A1RECQLCA1CA2 | |
| SCHEMBL30169768 | 0.80 | CYP3A4 (0.49) | CYP3A4ALDH1A1RECQLNPC1MAPT | |
| SCHEMBL4623711 | 0.80 | CYP3A4 (0.49) | CYP3A4ALDH1A1RECQLNPC1MAPT | |
| SCHEMBL10940362 | 0.78 | CYP3A4 (0.54) | CYP3A4HSD17B10ALDH1A1TTRTSHR | |
| SCHEMBL6410362 | 0.78 | GAA (0.49) | CYP3A4HSD17B10ALDH1A1TSHRCA1 | |
| SCHEMBL272067 | 0.78 | HSD17B10 (0.55) | CYP3A4HSD17B10ALDH1A1TTRTSHR | |
| SCHEMBL1047515 | 0.78 | ALDH1A1 (0.56) | CYP3A4HSD17B10ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178249-B | Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof | 北京亦农生物科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-116178249-A | Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof | 北京亦农生物科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-116178249-B | Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof | 北京亦农生物科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116178249-A | Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof | 北京亦农生物科技有限公司 | 2023-05-30 | — | — | CN | disclosed |