Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15052308 | 0.86 | AAK1 (0.38) | AAK1S1PR1S1PR3NPC1ALDH1A1 | |
| SCHEMBL29217774 | 0.81 | MET (0.32) | — | |
| SCHEMBL1180451 | 0.80 | AAK1 (0.41) | AAK1S1PR1S1PR3SMN1; SMN2 | |
| SCHEMBL29026433 | 0.79 | HCRTR1 (0.33) | — | |
| SCHEMBL29026440 | 0.76 | HCRTR1 (0.33) | — | |
| SCHEMBL323430 | 0.74 | AAK1 (0.38) | AAK1S1PR1S1PR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL29026448 | 0.72 | ATM (0.43) | ALDH1A1 | |
| SCHEMBL29026456 | 0.72 | — | — | |
| SCHEMBL1404066 | 0.71 | AAK1 (0.42) | AAK1S1PR1S1PR3SMN1; SMN2 | |
| SCHEMBL2185802 | 0.70 | RXRA (0.32) | RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157394-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-05-23 | — | — | CN | disclosed |