Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | KAT7 | O95251 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29026421 | 0.83 | GSK3B (0.42) | PDPK1CTSKCTSCGSK3BDYRK1A | |
| SCHEMBL25382912 | 0.79 | KAT7 (0.38) | MAPK1PDPK1CTSKCTSCGSK3B | |
| SCHEMBL30391950 | 0.75 | GSK3B (0.36) | MAPK1PDPK1CTSKCTSCGSK3B | |
| SCHEMBL24208429 | 0.75 | GSK3B (0.36) | MAPK1PDPK1CTSKCTSCGSK3B | |
| SCHEMBL24208434 | 0.73 | PRMT5 (0.41) | MAPK1PDPK1PRMT5WDR77PDK2 | |
| Hydrochloric Acid SCHEMBL30357695 | 0.72 | PRMT5 (0.40) | MAPK1PDPK1PRMT5WDR77PDK2 | |
| SCHEMBL30392205 | 0.71 | AAK1 (0.33) | PDPK1CTSKCTSCGSK3BDYRK1A | |
| Hydrochloric Acid SCHEMBL30391744 | 0.70 | PDPK1 (0.34) | MAPK1PDPK1GSK3BDYRK1APRMT5 | |
| SCHEMBL24208363 | 0.68 | ALDH1A1 (0.41) | GSK3BDYRK1AFGFR1DDR2 | |
| SCHEMBL24214149 | 0.67 | GSK3B (0.41) | MAPK1GSK3BDYRK1APDK2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157394-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-05-23 | — | — | CN | disclosed |