Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 4/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29026441 | 0.83 | MAPK1 (0.35) | GSK3BDYRK1APRMT5WDR77PDPK1 | |
| SCHEMBL29190392 | 0.81 | PTGS2 (0.38) | GSK3BDYRK1AICMTSCN9A | |
| SCHEMBL25335447 | 0.79 | GSK3B (0.46) | GSK3BDYRK1APRMT5WDR77PDPK1 | |
| SCHEMBL28918253 | 0.75 | HTR1D (0.42) | — | |
| SCHEMBL24208378 | 0.74 | GSK3B (0.43) | GSK3BDYRK1APRMT5WDR77PDPK1 | |
| SCHEMBL30526851 | 0.74 | GSK3B (0.43) | GSK3BDYRK1APRMT5WDR77PDPK1 | |
| SCHEMBL24214870 | 0.73 | GSK3B (0.45) | GSK3BDYRK1APRMT5WDR77MKNK1 | |
| SCHEMBL4377009 | 0.72 | MTNR1A (0.41) | ICMT | |
| SCHEMBL23207914 | 0.72 | PRMT5 (0.50) | GSK3BDYRK1APRMT5WDR77PDPK1 | |
| Hydrochloric Acid SCHEMBL25381509 | 0.71 | PRMT5 (0.49) | GSK3BDYRK1APRMT5WDR77PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116157394-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-05-23 | — | — | CN | disclosed |