Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.85 |
| ▸ | NPC1 | O15118 | 10/20 | 0.85 |
| ▸ | RAB9A | P51151 | 9/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.85 |
| ▸ | NPBWR1 | P48145 | 9/20 | 0.85 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.85 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.85 |
| ▸ | RELA | Q04206 | 4/20 | 0.85 |
| ▸ | CASP3 | P42574 | 2/20 | 0.85 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.85 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.85 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.85 |
| ▸ | POLB | P06746 | 2/20 | 0.85 |
| ▸ | HTT | P42858 | 5/20 | 0.79 |
| ▸ | MMP2 | P08253 | 4/20 | 0.79 |
| ▸ | MMP9 | P14780 | 4/20 | 0.79 |
| ▸ | MMP8 | P22894 | 4/20 | 0.79 |
| ▸ | MMP13 | P45452 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10117321 | 0.92 | NPBWR1 (1.00) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL29026603 | 0.89 | NPBWR1 (0.71) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL31154234 | 0.89 | NPBWR1 (0.71) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL5566191 | 0.88 | NPC1 (1.00) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL20982761 | 0.87 | NPC1 (0.97) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL20982700 | 0.85 | NPC1 (0.94) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL31357888 | 0.85 | RAB9A (0.81) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL2251258 | 0.85 | MEN1 (1.00) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL20982512 | 0.83 | MEN1 (0.96) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 | |
| SCHEMBL363703 | 0.83 | MEN1 (1.00) | MAPTNPC1RAB9ASMN1; SMN2NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375651-B | Preparation method of 2- (4-aminophenyl) -5-aminobenzimidazole | 山东大学 | 2024-07-19 | — | — | CN | claimed |
| CN-116375651-A | Preparation method of 2- (4-aminophenyl) -5-aminobenzimidazole | 山东大学 | 2023-07-04 | — | — | CN | claimed |
| CN-116375651-B | Preparation method of 2- (4-aminophenyl) -5-aminobenzimidazole | 山东大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-116375651-B | Preparation method of 2- (4-aminophenyl) -5-aminobenzimidazole | 山东大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-116375651-A | Preparation method of 2- (4-aminophenyl) -5-aminobenzimidazole | 山东大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116375651-A | Preparation method of 2- (4-aminophenyl) -5-aminobenzimidazole | 山东大学 | 2023-07-04 | — | — | CN | disclosed |