Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24961335 | 0.86 | HRH1 (0.42) | HRH1KCNH2NOTUMGAAMAPT | |
| SCHEMBL29751644 | 0.71 | JAK2 (0.38) | LMNA | |
| SCHEMBL29191559 | 0.68 | MEN1 (0.31) | HRH1KCNH2MEN1KMT2A | |
| SCHEMBL22369257 | 0.68 | CYP2D6 (0.45) | HRH1KCNH2MEN1LMNAKMT2A | |
| SCHEMBL15174490 | 0.68 | CYP2D6 (0.45) | HRH1KCNH2MEN1LMNAKMT2A | |
| SCHEMBL29191541 | 0.68 | GAA (0.36) | HRH1KCNH2NOTUMGAAMAPT | |
| SCHEMBL11152177 | 0.68 | — | — | |
| SCHEMBL16401424 | 0.67 | GAA (0.44) | GAA | |
| SCHEMBL174399 | 0.67 | — | — | |
| SCHEMBL11486690 | 0.67 | ADRA2C (0.46) | KCNH2NOTUMGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789146-B | Chemokine receptor modulators and uses thereof | 拉普特医疗公司 | 2023-04-18 | — | — | CN | disclosed |