Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30505940 | 1.00 | CRBN (0.38) | CRBNPDK2METGABRA1GABRG2 | |
| SCHEMBL29746895 | 0.85 | MAPK1 (0.40) | CRBNPDK2CA12CA1CA2 | |
| SCHEMBL24401254 | 0.85 | MAPK1 (0.40) | CRBNPDK2CA12CA1CA2 | |
| SCHEMBL29746865 | 0.79 | HCAR2 (0.36) | — | |
| SCHEMBL24401253 | 0.79 | HCAR2 (0.36) | — | |
| SCHEMBL2132762 | 0.69 | GABRG2 (0.41) | METGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL27974850 | 0.69 | GABRA1 (0.35) | CRBNMETGABRA1GABRG2GABRB3 | |
| SCHEMBL5385127 | 0.67 | CA12 (0.38) | METGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL27432514 | 0.67 | GABRA1 (0.39) | METGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL21094068 | 0.66 | TDP1 (0.39) | METGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375683-A | Diazole derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |