Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | BMX | P51813 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29026946 | 0.82 | BRD4 (0.35) | ZAP70GAATSHRCHEK1AURKA | |
| SCHEMBL23346719 | 0.67 | PRKCI (0.56) | PRKCIGAAGLACHEK1AURKA | |
| SCHEMBL30038986 | 0.67 | CHEK1 (0.38) | POLBCHEK1AURKANTRK1CDK1 | |
| SCHEMBL27562099 | 0.66 | BRD4 (0.35) | BRPF1BRD4TAF1CREBBPCECR2 | |
| SCHEMBL16021148 | 0.65 | BRD4 (0.34) | GAABRPF1BRD4TAF1CREBBP | |
| SCHEMBL26831959 | 0.65 | BRD4 (0.34) | GAAPOLBBRPF1BRD4TAF1 | |
| SCHEMBL26800825 | 0.65 | BRD9 (0.39) | ZAP70CDK2BRPF1BRD4TAF1 | |
| SCHEMBL13460182 | 0.64 | RAB9A (0.45) | TSHRPOLBMEN1KMT2AMAPT | |
| SCHEMBL13139309 | 0.64 | KDM4E (0.41) | ZAP70CDK2BRPF1BRD4TAF1 | |
| SCHEMBL2032060 | 0.64 | JAK2 (0.44) | PRKCIZAP70GAATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375683-A | Diazole derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |