Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | BMX | P51813 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29027066 | 0.82 | PRKCI (0.40) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL25898037 | 0.80 | TAF1 (0.38) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL31298852 | 0.76 | GRM2 (0.40) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL26831959 | 0.72 | BRD4 (0.34) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL25899446 | 0.70 | BRD4 (0.38) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL29026813 | 0.69 | CHEK1 (0.43) | CHEK1KDM4EALDH1A1GAANPSR1 | |
| SCHEMBL1851546 | 0.68 | HTT (0.45) | BRD4BRD9LMNAHTTHCAR1 | |
| SCHEMBL29348956 | 0.68 | MAPT (0.33) | MAPTKDM4EHDAC6NPSR1EPRS1 | |
| SCHEMBL29809118 | 0.67 | CCNE2 (0.41) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL582859 | 0.67 | CCNE2 (0.41) | BRD4TAF1BRPF1CREBBPCECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375683-A | Diazole derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |