SCHEMBL29027157

SCHEMBL29027157

CC(C)CCC(CCC(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 15/20 0.59
CYP1A2 P05177 1/20 0.54
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
GRM3 Q14832 2/20 0.50
NAALAD2 Q9Y3Q0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9115232 0.88 SLC1A3 (0.64) FOLH1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL13726298 0.88 FOLH1 (0.73) FOLH1GRM3NAALAD2
SCHEMBL3396224 0.85 FOLH1 (0.67) FOLH1CYP1A2GRM3
SCHEMBL108166 0.85 FOLH1 (0.76) FOLH1GRM3NAALAD2
SCHEMBL27996973 0.83 FOLH1 (0.73) FOLH1GRM3NAALAD2
SCHEMBL29060942 0.83 FOLH1 (0.73) FOLH1GRM3NAALAD2
SCHEMBL5054744 0.83 FOLH1 (0.61) FOLH1CYP1A2GRM3NAALAD2
SCHEMBL2015915 0.82 FOLH1 (0.58) FOLH1CYP1A2SLC1A3SLC1A2GRM3
SCHEMBL9816501 0.81 SLC1A3 (0.48) FOLH1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL21296128 0.81 CYP1A2 (0.59) FOLH1CYP1A2GRM3NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110803993-B Synthetic method of pregabalin intermediate ethyl 2-carboxyethyl-3-nitromethylene-5-methylhexanoate 陕西科技大学 2023-06-30 CN disclosed