Phthalic Acid

Phthalic Acid

SCHEMBL29027367

C=CCNc1nc(N)nc(N)n1.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNA2 P20248 3/20 0.45
CDK2 P24941 3/20 0.45
CCNE1 P24864 1/20 0.45
KMT2A Q03164 2/20 0.41
HCAR3 P49019 1/20 0.40
ALDH1A1 P00352 3/20 0.40
ALOX15 P16050 2/20 0.40
CYP1A2 P05177 1/20 0.39
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HCRTR1 O43613 1/20 0.38
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL5690331 0.79 GAA (0.43) CCNA2CDK2CCNE1KMT2AALDH1A1
SCHEMBL276285 0.79 GAA (0.46) KMT2AALDH1A1CYP1A2TSHRMAPK1
SCHEMBL8058873 0.78 NPSR1 (0.59) KMT2AALDH1A1NPSR1MAPTKDM4E
Phthalic Acid SCHEMBL29234747 0.78 ALDH1A1 (0.67) ALDH1A1ALOX15HPGDMAPTKDM4E
Phthalic Acid SCHEMBL581001 0.78 ALDH1A1 (0.67) ALDH1A1ALOX15HPGDMAPTKDM4E
SCHEMBL11664446 0.77 NPSR1 (0.66) ALOX15NPSR1TSHRMAPK1
SCHEMBL2268712 0.76 POLB (0.46) KMT2AALDH1A1CYP1A2TSHRMAPK1
Phthalic Acid SCHEMBL11333396 0.74 ALDH1A1 (0.56) KMT2AALDH1A1ALOX15CYP1A2HPGD
SCHEMBL29915668 0.73 ALDH1A1 (0.57) KMT2AHCAR3ALDH1A1ALOX15CYP1A2
SCHEMBL587283 0.73 ALDH1A1 (0.57) KMT2AHCAR3ALDH1A1ALOX15CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234793-A Stabilizer based on syringic acid, vanillic acid, isovanillic acid or 5-hydroxyveratric acid, plastic composition, method for stabilizing a plastic composition and stabilizer composition 弗劳恩霍夫应用研究促进协会 2024-06-21 CN claimed
CN-117222700-A Use of a stabilizer composition for stabilizing organic materials, stabilizer composition, masterbatch, composition, molding compound for molded parts, method for oxidative stabilization, thermal stabilization, photochemical stabilization of thermoplastics, and use of a composition 弗劳恩霍夫应用研究促进协会 2023-12-12 CN claimed
CN-116390981-A Use of eugenol derivatives as stabilizers, organic materials and eugenol derivatives 弗劳恩霍夫应用研究促进协会 2023-07-04 CN claimed
CN-116368185-A Use of dehydrobisphenol, eugenol oligomers and/or eugenol polymers for stabilizing organic materials, stabilized plastic compositions, stabilizer compositions and method for stabilizing organic materials 弗劳恩霍夫应用研究促进协会 2023-06-30 CN claimed
CN-118234793-A Stabilizer based on syringic acid, vanillic acid, isovanillic acid or 5-hydroxyveratric acid, plastic composition, method for stabilizing a plastic composition and stabilizer composition 弗劳恩霍夫应用研究促进协会 2024-06-21 CN disclosed
CN-117222700-A Use of a stabilizer composition for stabilizing organic materials, stabilizer composition, masterbatch, composition, molding compound for molded parts, method for oxidative stabilization, thermal stabilization, photochemical stabilization of thermoplastics, and use of a composition 弗劳恩霍夫应用研究促进协会 2023-12-12 CN disclosed
CN-116390981-A Use of eugenol derivatives as stabilizers, organic materials and eugenol derivatives 弗劳恩霍夫应用研究促进协会 2023-07-04 CN disclosed
CN-116368185-A Use of dehydrobisphenol, eugenol oligomers and/or eugenol polymers for stabilizing organic materials, stabilized plastic compositions, stabilizer compositions and method for stabilizing organic materials 弗劳恩霍夫应用研究促进协会 2023-06-30 CN disclosed